Thallium reinjection demonstrates viable myocardium in regions with reverse redistribution.

Thallium reinjection demonstrates viable myocardium in regions with reverse redistribution.

BACKGROUND The clinical significance and pathophysiological mechanisms of reverse redistribution on stress-redistribution thallium-201 myocardial scintigraphy in patients with chronic coronary artery disease are unclear. Recent studies have shown that thallium-201 reinjection is a useful technique for the detection of myocardial viability in chronic coronary artery disease. In this investigatio...

Viable myocardium and reinjection of thallium.

Stress-Redistribution-Reinjection and Rest-Redistribution Thallium Imaging for Assessing Viable Myocardium Comparison With Metabolic Activity by Positron Emission Tomography

Background. Stress thallium scintigraphy provides important diagnostic and prognostic information in patients with coronary artery disease by demonstrating regional myocardial ischemia. However, if the clinical question being addressed is whether a region is viable and not whether there is inducible ischemia, then it may be more reasonable to perform rest-redistribution imaging rather than stre...

Thallium reinjection after stress-redistribution imaging. Does 24-hour delayed imaging after reinjection enhance detection of viable myocardium?

BACKGROUND Thallium reinjection immediately after conventional stress-redistribution imaging improves the detection of viable myocardium, as many myocardial regions with apparently "irreversible" thallium defects on standard 3-4-hour redistribution images manifest enhanced thallium uptake after reinjection. Because the 10-minute period between reinjection and imaging may be too short, the prese...

Regional thallium uptake in irreversible defects.

Background. Thallium reinjection immediately after stress-redistribution imaging identifies ischemic but viable myocardium in as many as 50%o of the regions characterized by conventional redistribution imaging as irreversibly injured. However, we have previously shown that some regions in which irreversible defects persist despite reinjection are metabolically active, and hence viable, by posit...